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. 2013 Oct;41(10):1813–1824. doi: 10.1124/dmd.113.053108

TABLE 1.

Km and kcat values for the CYP2B6-catalyzed deethylation of EFC in the presence of RTV

The EFC concentrations used were 1, 2.5, 5, 10, 25, and 50 μM.

RTV Km kcat
μM μM min−1
0 1.83 0.80
0.1 2.05 0.67
0.3 2.47 0.54
0.6 2.68 0.44
1.0 4.00 0.37