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. 2013 Oct;347(1):7–19. doi: 10.1124/jpet.113.205245

Fig. 3.

Fig. 3.

Spinal TY027 attenuates SNL-induced hypersensitivities in rats. (A) Nerve injury induces a significant decrease in thermal PWLs that are reversed by spinal administration of TY027 in a dose-dependent and biphasic manner (*P ≤ 0.05; n = 10–19). (B) Nerve injury induces a significant decrease in mechanical PWTs that are reversed by spinal administration of TY027 in a dose-dependent and biphasic manner (*P ≤ 0.05; n = 10–19). Arrows indicate the time of compound or vehicle administration (in 5 µl).