TABLE 2.
Treatment (Dose) |
Symptom |
||||
---|---|---|---|---|---|
Teeth Chattering |
Grooming Bouts |
Wet-Dog Shakes |
Weight Loss |
Diarrhea |
|
g | N/Ntotal | ||||
Saline | 0.00 (0.00) | 5.00 (1.26) | 0.00 (0.00) | 0.33 (0.49) | 0/6 |
MS (3 mg/kg) | 24.33 (9.33)* | 4.22 (1.75) | 1.11 (0.39)* | 3.79 (0.32)** | 8/9 |
DTS | 0.14 (0.14) | 4.71 (1.48) | 0.14 (0.14) | 2.86 (0.63) | 1/7 |
TY027 (10 mg/kg) | 0.11 (0.11)‡ | 2.89 (0.79) | 0.00 (0.00)‡ | 1.89 (0.45)‡ | 0/9 |
P ≤ 0.05; **P ≤ 0.01 compared with vehicle; ‡P ≤ 0.05 compared with MS determined by ANOVA, post-hoc Student-Newman-Keuls.