Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Sep 17;62(10):3500–3513. doi: 10.2337/db13-0266

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

PMC Copyright notice

FIG. 3. — Decreased P-IR and total FOXO1 levels in an HFS diet. A: Immunostaining for insulin (green), glucagon (blue), and tyrosine P-IR (red) in islets of monkeys after 24 months on SD (top panel), HFS diet (middle panel), or HFS+Resv diet (bottom panel). Scale bar = 20 µm. B: Quantitation of signal intensity for P-IR. Data are shown as the mean ± SEM. *P < 0.05. C: Immunostaining for insulin (green), TO-PRO-3 (blue), and total FOXO1 (red) in islets of monkeys after 24 months on SD (top panel), HFS (middle panel), or HFS+Resv (bottom panel) diets. Scale bar = 20 µm. D and E: Quantitation of signal intensity (D) and mRNA levels (E) for FOXO1. Data are shown as the mean ± SEM. *P < 0.05.