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IT dissociates ileal and hepatic FXR expression/activity. A: Ileal mRNA relative expression of Fxr, Ostα, and Fgf15. B: Hepatic mRNA relative expression of Pepck, G6pc, Pgc1α, and Gr. C: Hepatic mRNA expression of Fxr, Shp, Ntcp, Cyp7α1, Cyp7β1, Cyp8β1, Cyp27α1, Bsep, and Ostα. Values are normalized relative to Gapdh mRNA and are expressed relative to those of sham-operated rats, which were arbitrarily set to 1. Data are mean ± SE (n = 5 per group). *P < 0.05 IT vs. sham.
