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Effect of GFT505 on human skeletal muscle gene expression. Gene (mRNA) expression in skeletal muscle biopsy specimens at the end of the first 8-week treatment period with GFT505 (80 mg/day) or placebo (n = 9/group). mRNA levels were measured by quantitative PCR. Values (means ± SD) are normalized to the expression of 18S and are expressed relative to placebo group. PCB, placebo group.
