FIGURE 2.

No increase in cell death of progenitor cells in vitro or in vivo under radixin inhibition. Paired results from four different experiments showed no significant difference in thepercentage of cells that migrated out from SVZ explant cultures being AnnexinV postitive (A) or PI positive (B) under different concentrations of the radixin inhibitor DX52-1 (Vehicle, 50, 100, and 250 nM). (C) The number of TUNEL positive cells was quantified per volume in the RMS after 4 days of intracerebroventricular infusion of vehicle or DX52-1 (n = 5).