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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Ther Drug Monit. 2013 Oct;35(5):631–642. doi: 10.1097/FTD.0b013e31828f5088

Table 5.

Summary of associations between bias and the 6 factors, and between error and the 6 factors.

Factor Bias Error
Model 2A: NC=WIV Model 2B: NC=FT Model 3A: NC=WIV Model 3B: NC=FT
Overall F-test Summary Overall F-test p-value Summary KW test
p-value
Summary KW test
p-value
Summary
ARV <0.001 Highest estimated bias for DRV and RGV; many statistically significant pairwise differences. 0.253 -- <0.001 Many; highest (ranks of) errors for DRV and RGV. <0.001 {DRV,NVP} > {RGV,RTV,ZDV}, and DRV>MVC.
Lab <0.001 Labs 6 and 7 have higher recoveries than most other labs. Lab 2 has lowest recovery(below 100%). <0.001 Labs 6 and 7 have higher recoveries than most other labs. Lab 2 has lowest recovery (below 100%). <0.001 {3, 6, 7} >all others. <0.001 {3, 6, 7} >all others, and 3>6.
WIV category, L/M/H within analyte <0.001 Low & Medium > High 0.099 -- 0.872 -- 0.563 --
WIV category, “power of ten” 0.005 Despite p<0.05, no pairwise differences were statistically significant. 0.907 -- 0.125 -- 0.941 --
Round 0.093 -- 0.413 -- <0.001 Round 23 > 24 & 25. 0.094 --

KW = Kruskal-Wallis test. ARV = antiretroviral drug, WIV = weighed-in value. L/M/H = low/medium/high. NC = nominal concentration. FT = final target.