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. 2013 May 31;22(20):4074–4083. doi: 10.1093/hmg/ddt257

Figure 4.

Figure 4.

RG3039 does not change ventral root axon number, but does improve motor neuron somal synaptic input. (A) Image of L1 ventral roots from control littermate, vehicle-treated SMA and RG3039-treated SMA mice. (B) Quantification of ventral root number. (C) Representative images of motor neurons (red = ChAT) and somal VGLUT1 synapses (green = VGLUT1) from control littermate, vehicle-treated SMA and RG3039-treated SMA mice. (D) Quantification of VGLUT1 motor neuron somal synapses (*P < 0.05, n = 3 per group).