Figure 2. A-F: Cytomorphology and immunophenotype of the PEL cells. Large, atypical lymphoid cells exhibit rounded nuclei, coarsely granular chromatin, and a moderate amount of cytoplasm. Apoptotic bodies and necrotic debris are seen throughout the smears. Many of the smudged, small nuclei represent pyknosis (individual cell necrosis-not small lymphocytes (H&E, 1000×) (A-F a. Mitotic figures were abundant (A). Expression of CD30 (B), CD138 (C), epithelial membrane antigen (EMA) (D), and HHV-8 (E) in tumor cells (immunoperoxidase, 1000×). Cytomorphology of the PEL cells in the smears of ascites specimen (F).