Simple schematics of three example biological protein materials. A) Intermediate filaments, B) collagenous tissues, and C) amyloid proteins revealing their hierarchical makeup, illustrating potential material candidates benefiting from a materiomic perspective. Materiomics focuses on the development of integrated multiscale material models, focused on mechanical behavior at deformation and failure, fundamentally linked to cross-scale interactions from nano to macro. Copyright © 2010. Buehler and Yung. Adapted with permission from Buehler MJ, Yung YC. How protein materials balance strength, robustness and adaptability. HFSP J. 2010;4(1):26–40.5