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The definitions of acute and chronic GvHD
| Category | Manifestation time | aGvHD features | cGvHD features |
|---|---|---|---|
| aGvHD | |||
| Classic | ≤100 d | Yes | No |
| Persistent, recurrent, late onset | >100 d | Yes | No |
| cGvHD | |||
| Classic | No time limit | No | Yes |
| Overlap syndrome | No time limit | Yes | Yes |
Abbreviations: GvHD, graft-versus-host disease; aGvHD, acute GvHD; cGvHD, chronic GvHD.
