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. 2013 Sep 10;94(5):320–328. doi: 10.1111/iep.12036

Figure 4.

Figure 4

PrPSc labelling in hippocampus and midbrain of each inoculation route. Stellate-type immunolabelling in i.c. (a) oral (c) and i.g. (e) inoculated mice in the dentate gyrus of the hippocampus. The periaquaductal grey is encased by a surrounding layer of granular deposition in i.c. (b) oral (d) and i.g. (f) administered mice. (g) and (h) are negative controls; i.c., intracerebral inoculation (20 μl dose); oral, oral inoculation (500 μl dose); i.g.1, intragastric inoculation (500 μl dose).