Table 2.
Comparison of the prevalence of Brugada-type ECG in different ethnic populations
| Study | Year of publication | Origin | N | Males (%) | Age (years) | Nature of population | Sex ratio of BS M/F | Prevalence of BS Type 1 (%) | Prevalence of all BS types (%) | FU | Sudden death during FU |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Asian population | |||||||||||
| Furuhashi et al11 | 2001 | Japan | 8612 | 69.5 | 49.2 (22–84) |
Health examination | 11/1 | 0.05 | 0.14 | NA | NA |
| Mastuo et al12 | 2001 | Japan | 4788 | 40.8 | 45 ± 10.5 | Health examination | 27/5 | NA | 0.14 | 41 years | 5 |
| Atarashi et al13 | 2001 | Japan | 10,000 | 89.1 | 42 ± 9 | Health examination | 16/0 | NA | 0.16 | NA | NA |
| Yamakawa et al14 | 2004 | Japan | 20,387 | 51.1 | 9.7 ± 3.2 | School children | 1/1 | 0.0049 | 0.0098 | NA | NA |
| Yoshinaga et al15 | 2004 | Japan | 7022 | 100 | 15 | Male adolescents | 7 | 0.06 | 0.1 | NA | NA |
| Oe etal16 | 2005 | Japan | 21,944 | 41.4 | 6–7 | Children, CBP | 2/2 | 0.005 | 0.02 | 6.8 ± 1 years | 0 |
| Babaee Bigi et al17 | 2007 | Iran | 3895 | 46 | 38.2 ± 11.9 | Tertiary hospital | 66/44 | 0.54 | 2.56 | NA | NA |
| Gervacio-Domingo et al18 | 2008 | Philippines | 3907 | NA | ≥20 | Healthy subjects | 68/26 | 0.2 | 2.1 | NA | NA |
| Wajed et al19 | 2008 | Pakistan | 1100 | 64.7 | NA | Healthy young students | 7/2 | NA | 0.8 | NA | NA |
| Tsuji et al20 | 2008 | Japan | 13,904 | 26 | 58 ± 10 | Health examination | 80/18 | 0.26 | 0.7 | 7.8 ± 1.6 years | 1 |
| Sidik et al21 | 2009 | China(br/)Singapore | 392 | 55.9 | 49.9 ± 19.1 | Tertiary medical center | 27/1 | 4.8 | 7.1 | 30.4 person-years | 0 |
| European population | |||||||||||
| Hermida et al22 | 2000 | France | 1000 | 63.2 | 39 ± 10 | Normal subjects | 52/9 | 0.1 | 0.61 | 49 ± 30 months | 0 |
| Viskin et al23 | 2000 | Israel | 592 | 58.4 | 36 ± 10 | Tertiary hospital | NA | 0 | NA | NA | |
| Bianco et al24 | 2001 | Italy | 155 | 100% | 30.9 ± 10.1 | Competitive athletes | 12 | 7.7 | NA | NA | NA |
| Junttila et al25 | 2004 | Finland | 2749 | 100% | 18–30 | Finnish air force | NA | 0 | 0.61 | 19 ± 2 years | 0 |
| Blangy et al26 | 2005 | France | 35,309 | 47% | 37.2 | Health examination | 14/6 | 0.016 | 0.05 | 30 months | 0 |
| Bozkurt et al27 | 2006 | Turkey | 1238 | 77.8% | 38.9 ± 17.6 | Tertiary hospital and university students | 5/1 | 0.08 | 0.48 | NA | NA |
| Letsas et al28 | 2007 | Greece | 11,488 | 57.7% | 15–98 | Tertiary hospital | 23/2 | 0.02 | 0.22 | 24 ± 12 months | 0 |
| Gallagher et al29 | 2008 | Italy | 12,012 | 90.8% | 29 ± 9 | Healthy subjects | 23/0 | 0.016 | 0.19 | 10.1 ± 5.5 years | 1 patient/0.3% per patient of year FU |
| Sinner et al30 | 2009 | German | 4149 | 49% | 50.6 ± 13.9 | General population | 0 | 0 | 0 | NA | NA |
| American population | |||||||||||
| Monroe and Littman31 | 2000 | USA | 12,000 | NA | NA | Urban teaching hospital | NA | 0.016 | 0.43 | NA | NA |
| Greer and Glancy32 | 2003 | USA | 27,328 | NA | NA | Medical center | NA | 0 | 0.065 | NA | NA |
| Donohue and 33 | 2008 | USA | 1348 | NA | 52.7 ± 16.2 | Tertiary hospital | 1/1 | 0 | 0.14 | NA | NA |
| Patel et al34 | 2009 | USA | 162,590 | NA | NA | Tertiary medical center | 13/7 | 0.005 | 0.012 | NA | NA |
| North African population | |||||||||||
| This study | 2010 | Tunisia | 540 | 348 | 18.3 ± 2.4 | Athletes | 7/2 | 0 | 1.16 | NA | NA |
Abbreviations: BS, Brugada sign; FU, follow-up; F, female; M, male; NA, not available; CBP, community-based population.