Table 4.
One-way sensitivity analyses.
| Incremental costs | Incremental QALYs | Incremental $/QALY | |
|---|---|---|---|
| Sensitivity analysis by age and gender assuming the same risk of stroke for all starting ages | |||
|
| |||
| Males | |||
| Age | |||
| 55 | $8,330 | 0.146 | $57,167 |
| 60 | $8,365 | 0.145 | $57,846 |
| 65 | $8,539 | 0.144 | $59,194 |
| 70 | $8,630 | 0.141 | $61,120 |
| 75 | $8,787 | 0.135 | $65,129 |
| Females | |||
| Age | |||
| 55 | $8,330 | 0.146 | $57,088 |
| 60 | $8,365 | 0.145 | $57,765 |
| 65 | $8,548 | 0.144 | $59,219 |
| 70 | $8,637 | 0.141 | $61,142 |
| 75 | $8,793 | 0.135 | $65,147 |
| CHADS2 risk score | |||
| 0 | $9,259 | 0.135 | $68,822 |
| 1 | $8,941 | 0.139 | $64,412 |
| 2 | $8,539 | 0.144 | $59,194 |
| 3 | $7,952 | 0.152 | $52,214 |
| 4 | $7,242 | 0.162 | $44,652 |
| Time horizon | |||
| 3 years | $10,670 | 0.082 | $130,711 |
| 5 years | $8,539 | 0.144 | $59,194 |
| 10 years | $4,299 | 0.301 | $14,273 |
| 20 years | ($71) | 0.505 | AF ablation dominates |
| Discount rate | |||
| 0% | $7,995 | 0.162 | $49,308 |
| 3% | $8,335 | 0.151 | $55,211 |
| 5% | $8,539 | 0.144 | $59,194 |
| Restoring NSR has no impact on stroke risk | $10,019 | 0.116 | $86,129 |
| Disutility of AF health state | |||
| 0 | $8,539 | 0.038 | $221,839 |
| 0.02 | $8,539 | 0.084 | $101,083 |
| 0.04 | $8,539 | 0.130 | $65,454 |
| 0.06 | $8,539 | 0.176 | $48,396 |
| 0.08 | $8,539 | 0.222 | $38,390 |
| Annual probability of recurrence of AF after ablation | |||
| 0.00 | $8,230 | 0.153 | $53,831 |
| 0.01 | $8,317 | 0.150 | $55,276 |
| 0.02 | $8,403 | 0.148 | $56,743 |
| 0.03 | $8,486 | 0.146 | $58,233 |
| 0.04 | $8,569 | 0.143 | $59,745 |
| 0.05 | $8,650 | 0.141 | $61,280 |