Table 4.
The laboratory data of the patients in both naltrexone and placebo groups.
Total | NLTX | Placebo | P | ||||
---|---|---|---|---|---|---|---|
Mean ± SD | Median (range) | Mean ± SD | Median (range) | Mean ± SD | Median (range) | ||
WBC ×106 µL | 11.5 ± 3.9 | 11.0 (34 to 21.7) | 10.6 ± 34 | 10.1 (34 to 17) | 12.3 ± 42 | 11.4 (65 to 2.17) | 0.12† |
RBC ×106 µL | 4.62 ± 0.48 | 4.56 (3.87 to 5.9) | 4.68 ± 0.49 | 4.62 (3.87 to 5.52) | 4.56 ± 0.49 | 4.51 (3.91 to 5.9) | 0.40† |
Hb (mg/dL) | 13.1 ± 2.6 | 13.4 (1.3 to 16.6) | 13.7 ± 1.9 | 14.1 (9.1 to 16.2) | 12.5 ± 3.1 | 12.4 (1.3 to 16.6) | 0.10† |
Hct (%) | 40.4 ± 4.6 | 39 (30.1 to 49.8) | 40.8 ± 5 | 40.3 (30.1 to 48.4) | 40 ± 4.3 | 39 (34 to 49.8) | 0.64‡ |
Platelet ×103 µL | 225 ± 89 | 225 (46 to 599) | 233 ± 100 | 232 (97 to 599) | 217 ± 79 | 220 (46 to 396) | 0.53† |
Blood sugar (mg/dL) | 117 ± 59 | 106 (50 to 317) | 101 ± 41 | 91 (53 to 197) | 133 ± 70 | 118 (50 to 317) | 0.03‡ |
Blood urea (mg/dL) | 27 ± 12 | 24 (15 to 69) | 25 ± 8 | 24 (15 to 47) | 29 ± 14 | 26 (15 to 69) | 0.35‡ |
Creatinine (mg/dL) | 1 ± 0.4 | 0.9 (0.6 to 3) | 0.9 ± 0.2 | 0.9 (0.6 to 1.5) | 1.1 ± 0.5 | 0.9 (0.6 to 3) | 0.13‡ |
SGOT (U/L) | 32 ± 37 | 22 (11 to 241) | 22 ± 11 | 18 (12 to 63) | 41 ± 49 | 25 (11 to 241) | 0.04‡ |
SGPT (U/L) | 28 ± 31 | 18 (5 to 167) | 24 ± 22 | 16 (10 to 105) | 32 ± 38 | 21 (5 to 167) | 0.58‡ |
LDH (U/L) | 519 ± 394 | 422 (216 to 2780) | 526 ± 514 | 416 (290 to 2780) | 514 ± 243 | 422 (216 to 1324) | 0.26‡ |
CPK (U/L) | 387 ± 914 | 110 (50 to 4450) | 105 ± 37 | 99 (59 to 170) | 656 ± 1231 | 144 (50 to 4450) | 0.04† |
ALP (U/L) | 180 ± 61 | 175 (11 to 320) | 177 ± 53 | 178 (98 to 310) | 182 ± 69 | 172 (11 to 320) | 0.80† |
Na (mEq/L) | 163 ± 169 | 139 (132 to 1346) | 187 ± 241 | 139 (132 to 1346) | 140 ± 3 | 140 (136 to 147) | 0.73‡ |
K (mEq/L) | 4 ± 0.4 | 4 (3.4 to 4.8) | 4 ± 0.4 | 4 (3.4 to 4.6) | 4.1 ± 0.4 | 4.1 (3.4 to 4.8) | 0.17† |
Bili. T (mg/dL) | 0.6 ± 0.3 | 0.5 (0 to 1.4) | 0.6 ± 0.3 | 0.5 (0 to 1.4) | 0.6 ± 0.3 | 0.5 (0 to 1.4) | 0.62‡ |
Bili. D (mg/dL) | 0.2 ± 0.1 | 0.2 (0.1 to 1) | 0.2 ± 0.2 | 0.2 (0.1 to 1) | 0.2 ± 0.1 | 0.1 (0.1 to 0.3) | 0.02‡ |
†Based on Student's t-test. ‡Based on Mann-Whitney U test.