Table 3.
Final Linear Mixed Effects Models by Neurocognitive Outcome
| Outcome and Covariate | Coefficient Estimate | P |
|---|---|---|
| Intercept | ||
| PS | ||
| Intercept | 17.7137 | < .001 |
| Sex (female) | 2.3943 | .0343 |
| AgeDx | 0.0569 | .6550 |
| Risk (AR) | −1.6766 | .1871 |
| Baseline PS | 0.8056 | < .001 |
| WM | ||
| Intercept | 11.7845 | .0032 |
| Risk (AR) | 0.07723 | .9561 |
| Baseline WM | 0.8889 | < .001 |
| BA | ||
| Intercept | 7.7564 | .0352 |
| Risk (AR) | 1.1723 | .3732 |
| Baseline BA | 0.9130 | < .001 |
| Slope | ||
| PS | ||
| Time | −1.9084 | .4863 |
| AgeDx × time | 0.4700 | < .001 |
| Risk (AR) × time | 3.2377 | .0025 |
| Baseline PS × time | −0.05897 | .0095 |
| WM | ||
| Time | 7.1803 | .002 |
| Risk (AR) × time | 2.4886 | .0036 |
| Baseline WM × time | −0.09911 | < .001 |
| BA | ||
| Time | 6.4692 | .0353 |
| Risk (AR) × time | 3.1663 | .006 |
| Baseline BA × time | −0.1007 | < .001 |
Abbreviations: AgeDx, age at diagnosis; AR, average risk; BA, broad attention; PS, processing speed; WM, working memory.