Table A2.
Final Linear Mixed Effects Models by Neurocognitive Outcome
| Outcome and Covariate | Coefficient Estimate | P |
|---|---|---|
| Intercept | ||
| DS | ||
| Intercept | 18.2232 | < .001 |
| Sex (female) | 3.2390 | .009 |
| Risk (AR) | −0.9460 | .4953 |
| AgeDx | 0.01305 | .9253 |
| Baseline DS | 0.8044 | < .001 |
| VM | ||
| Intercept | 17.3422 | < .001 |
| AgeDx | 0.1729 | .1880 |
| Risk (AR) | −1.9544 | .1254 |
| Baseline VM | 0.8078 | < .001 |
| NR | ||
| Intercept | 16.9023 | .0003 |
| Risk (AR) | 1.9593 | .1917 |
| Baseline NR | 0.8275 | < .001 |
| AWM | ||
| Intercept | 19.1009 | < .001 |
| Risk (AR) | −2.8034 | .0684 |
| Baseline AWM | 0.8359 | < .001 |
| AA | ||
| Intercept | 35.8948 | < .001 |
| Risk (AR) | −0.4888 | .7707 |
| Baseline AA | 0.6472 | < .001 |
| Parent education | 0.07832 | .7877 |
| PC | ||
| Intercept | 6.9547 | .0627 |
| Risk (AR) | 1.3093 | .2586 |
| Baseline PC | 0.9071 | < .001 |
| Slope | ||
| DS | ||
| Time | 4.2792 | .1899 |
| Risk (AR) × time | 2.6263 | .0250 |
| AgeDx × time | 0.3226 | .0062 |
| Baseline DS × time | −0.09653 | < .001 |
| VM | ||
| Time | 2.3106 | .2701 |
| AgeDx × time | 0.08636 | < .001 |
| Risk (AR) × time | 0.8310 | .0019 |
| Baseline VM × time | 0.01905 | .0080 |
| NR | ||
| Time | 11.2763 | < .001 |
| Risk (AR) × time | 1.8564 | .0491 |
| Baseline NR × time | −0.1341 | < .001 |
| AWM | ||
| Time | 8.1587 | < .001 |
| Risk (AR) × time | 3.1648 | < .001 |
| Baseline AWM × time | −0.1099 | < .001 |
| AA | ||
| Time | 5.1546 | .2667 |
| Risk (AR) × time | 3.3908 | .0152 |
| Baseline AA × time | −0.1746 | < .001 |
| Parent education × time | 0.5637 | .0182 |
| PC | ||
| Time | 10.3868 | .0226 |
| Risk (AR) × time | 3.0545 | .0321 |
| Baseline PC × time | −0.1383 | .0036 |
Abbreviations: AA, auditory attention; AgeDx, age at diagnosis; AR, average risk; AWM, auditory working memory; DS, decision speed; NR, numbers reversed; PC, pair cancellation; VM, visual matching.