Table 3.
Variable | Adjuvant FU Chemotherapy* (n = 653) |
Surveillance Colonoscopy (n = 2006) |
||||
---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | |
Demographic | ||||||
White | 1.23 | 0.77 to 1.97 | .40 | 1.32 | 1.01 to 1.73 | .04 |
Married | 1.30 | 0.90 to 1.88 | .16 | 1.00 | 0.82 to 1.22 | 1.00 |
Age at diagnosis, years | ||||||
< 55 | 1.70 | 0.86 to 3.38 | .13 | 1.12 | 0.77 to 1.62 | .55 |
55-64 | 1.03 | 0.65 to 1.62 | .91 | 1.20 | 0.93 to 1.53 | .16 |
65-74 | 1.15 | 0.71 to 1.87 | .57 | 1.47 | 1.14 to 1.89 | < .01† |
75+ (referent) | ||||||
Region | ||||||
North | 1.75 | 1.00 to 3.07 | .05 | 1.28 | 0.96 to 1.71 | .09 |
Central | 1.52 | 0.95 to 2.42 | .08 | 0.84 | 0.65 to 1.08 | .18 |
West | 1.30 | 0.79 to 2.14 | .31 | 1.01 | 0.77 to 1.33 | .93 |
South (referent) | ||||||
Comorbidity | ||||||
Liver disease | 0.28 | 0.04 to 2.11 | .22 | —‡ | ||
Rheumatoid disease or AIDS | 1.11 | 0.20 to 6.17 | .90 | 1.00 | 0.40 to 2.46 | .99 |
Renal disease | 0.68 | 0.22 to 2.14 | .51 | 0.87 | 0.49 to 1.56 | .65 |
Dementia or paralysis | 0.17 | 0.01 to 2.03 | .16 | —§ | ||
CHF, acute MI, CVD, or COPD | 0.82 | 0.53 to 1.25 | .35 | 0.84 | 0.67 to 1.06 | .14 |
Diabetes | 0.84 | 0.56 to 1.26 | .40 | 0.86 | 0.69 to 1.08 | .20 |
Stage at diagnosis | ||||||
I | 0.71 | 0.56 to 0.90 | < .01† | |||
II (referent) | ||||||
III | 0.97 | 0.77 to 1.24 | .83 |
Abbreviations: CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CVD, cardiovascular disease; FU, fluorouracil; MI, myocardial infarction; OR, odds ratio.
Stage is not included because only patients with stage III colorectal cancer were included per National Comprehensive Cancer Network guidelines.
Indicates statistical significance of P < .01.
Because of issues of perfect prediction with liver disease, 11 observations were excluded.
Because of perfect prediction with dementia/paralysis, five observations were excluded.