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Overview of heme oxygenase-1 in renal diseases. Heme oxygenase (HO)-1 induction prevents renal damage in diverse renal diseases, such as acute kidney injury (AKI), chronic kidney disease (CKD), diabetic nephropathy (Diabetes) and renal Transplant. Arrows followed by text indicate increase (↑) or decrease (↓). 1Requires further study. TGF: Transforming growth factor; SMA: Smooth muscle actin; CTGF: Connective tissue growth factor; CAN: Chronic allograft nephropathy.
