Table 2.
Inflammation markers, total homocysteine and cytokines in chronic renal failure patients
CRF 1 | CRF 2 | CRF 3 | CRF 4 | HD | PD | P | |
TNF-α (pg/mL) | 0.39 ± 0.03 | 3.81 ± 1.52 | 7.80 ± 2.76 | 10.04 ± 1.61 | 16.38 ± 5.52 | 14.04 ± 3.40 | 0.001 |
IL-1β (pg/mL) | 3.24 ± 0.10 | 3.57 ± 0.47 | 6.69 ± 1.02 | 7.76 ± 0.66 | 9.63 ± 3.50 | 6.51 ± 1.37 | 0.001 |
IL-6 (pg/mL) | 8.20 ± 0.22 | 8.79 ± 1.04 | 8.88 ± 0.71 | 9.66 ± 0.56 | 11.05 ± 3.59 | 10.15 ± 1.66 | 0.001 |
tHcy (μmol/L) | 8.05 ± 2.43 | 11.95 ± 5.26 | 20.16 ± 2.62 | 25.34 ± 3.93 | 32.27 ± 12.08 | 28.37 ± 4.98 | 0.001 |
CRP (mg/L) | 3.29 ± 2.33 | 5.54 ± 2.16 | 8.18 ± 3.33 | 13.5 ± 4.28 | 18.17 ± 6.38 | 17.97 ± 4.85 | 0.001 |
Fib (g/L) | 3.58 ± 0.82 | 4.51 ± 0.47 | 5.80 ± 1.21 | 6.05 ± 0.57 | 6.86 ± 1.06 | 5.91 ± 0.59 | 0.001 |
Ferritin (ng/mL) | 47.66 ± 25.24 | 51.12 ± 34.57 | 74.22 ± 43.18 | 83.83 ± 44.99 | 169.90 ± 62.16 | 90.08 ± 22.09 | 0.001 |
Transferrin (g/L) | 2.73 ± 0.47 | 2.41 ± 0.23 | 2.29 ± 0.37 | 2.03 ± 0.49 | 1.86 ± 0.39 | 1.78 ± 0.21 | 0.001 |
Data are presented as the mean ± SD. Statistically significant differences between all the groups (P < 0.001). TNF-α: Tumor necrosis factor-α; IL-1β: Interleukin-1β; IL-6: Interleukin-6; tHcy: Total homocysteine; CRP: C-reactive protein; Fib: Fibrinogen; HD: Hemodialysis; PD: Peritoneal dialysis.