Table 4.
Efficacy and effects on biopsy proven and glomerular filtration rate of the main minimization trials
| Calcineurin inhibitors | F-up (mo) | Acute rejection | Graft survival | Biopsy proven | Glomerular filtration rate | |
| OptiCept | CsA/TAC | 24 | Similar | Similar | Similar | Similar |
| CAESAR | CsA | 12 | Similar | Similar | Similar | Similar |
| ASSET | TAC | 12 | Similar | Similar | Similar | Similar |
| Andres | CsA | 6 | Similar | Similar | Similar | Similar |
| 2309 | CsA | 12 | Similar | Similar | Similar | Similar |
| EVEREST | CsA | 36 | Similar | Similar | Similar | Similar |
| REFERENCE Study | CsA | 24 | Similar | Similar | Similar | Similar |
| De Sevaux | CsA | 6 | Similar | Similar | Similar | Similar |
CsA: Cyclosporine; TAC: Tacrolimus.