Table 5. Diagnostic Performance of Serum YB-1, AFP and YB-1+AFP for HCC.

Tumor Marker	Cut-Off Value, μg/L	HCC Patients		Controls, HBV + HBV Cirrhosis + Healthy		Sensitivity, %a	Specificity, %b	Accuracy, %c
		Cases	Positive	Cases	Positive
YB-1d	16.0	105	80	100	37	74.1	63.0	69.8
AFP	414	105	47	100	7	44.8	93.0	68.3
YB-1+AFP	ibid	105	94	100	38	89.5	62.0	76.1

^aSensitivity = TP/(TP + FN), where TP = true positive, FN = false negative

^bSpecificity = TN/(TN + FP), where TN = true negative, FP = false positive

^cAccuracy = (TP + TN)/(TP + FP + TN + FN)

^dAbbreviations: AFP, alpha-fetoprotein; HCC, hepatocellular carcinoma