Table 1.
Summary of key findings from the recent literature |
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Post-AKI diuretic therapy is associated with improved mortality in a population of critically ill patients with acute lung injury managed with a conservative fluid management approach. A negative fluid balance is the likely causal intermediate in the association between diuretics and mortality [24] |
In critically ill patients, dilution of the serum creatinine by fluid accumulation can lead to underestimation of the severity of AKI and may increase the time needed to identify a 50% increase in the serum creatinine [25] |
Patients with “unrecognized” AKI that is revealed after adjusting serum creatinine for positive fluid balance had a mortality rate significantly greater than those who did not have AKI either before or after adjustment for fluid balance or those who no longer had AKI after adjustment for fluid balance [26] |