Table 4.

Alternative PRRS vaccines

	Encoded ORF/GP	Immunogenicity		Protection		Ref.
		Antibody	CMI	Homologous	Heterologous
DNA vaccine	ORF1-7	+	+	+	ND	[45,46]
Subunit vaccine	GP5	Poor	Poor	-	ND	[47,48]
Synthetic peptide vaccine	GP5	-	-	ND	-	[13]
Adenovirus vector vaccine	GP3, 4, 5	+	+	ND	ND	[49-51]
PRV vector vaccine	GP5, M	+	+	+	ND	[52,53]
Poxvirus vector vaccine	GP3, 5, M	+	+	+	ND	[54,55]
TGEV vector vaccine	GP5, M	+	ND	+	ND	[56]
Alphavirus-derived replicon	GP5, M	+	+	+	+	[57]
Bacterial vector vaccine	GP5, M	+	-	+	ND	[58]
Insect cell-derived vaccine	ORF3, 5, 7	+	ND	+	ND	[59]
Plant-derived vaccine	GP5	+	+	ND	ND	[60,61]
Gene-deleted MLV (deleted15-mer nsp2 epitope)		+	ND	ND	ND	[65]

+: Success; -: Failure; ND: Not determined.