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. 2012 Feb 12;1(1):31–43. doi: 10.5501/wjv.v1.i1.31

Table 5.

Additional tests in the case of an isolated viral capsid antigen IgG pattern

Tests Advantages Disadvantages
EBV IgG immunoblotting Useful in distinguishing acute from past infection Individual antibody production; expensive
IgG avidity Useful in distinguishing acute from past infection Individual maturation. Not useful in newborns
Molecular biology Useful in distinguishing acute from past infection Uncorrected conservation of blood sample, presence of nucleasis; expensive; organisational problems
Heterophile antibodies Useful in distinguishing acute from past infection if positive; inexpensive and simple Not very sensitive (especially in children)
Anti-EA(D) IgG Of some use in distinguishing acute from past infection; costs the same as a screening test Not useful in at least 10% of cases

EBV: Epstein-Barr virus.