Table 5.
Tests | Advantages | Disadvantages |
EBV IgG immunoblotting | Useful in distinguishing acute from past infection | Individual antibody production; expensive |
IgG avidity | Useful in distinguishing acute from past infection | Individual maturation. Not useful in newborns |
Molecular biology | Useful in distinguishing acute from past infection | Uncorrected conservation of blood sample, presence of nucleasis; expensive; organisational problems |
Heterophile antibodies | Useful in distinguishing acute from past infection if positive; inexpensive and simple | Not very sensitive (especially in children) |
Anti-EA(D) IgG | Of some use in distinguishing acute from past infection; costs the same as a screening test | Not useful in at least 10% of cases |
EBV: Epstein-Barr virus.