Table 1.

Sample stress MR perfusion study protocol.

Sample stress MR perfusion study protocol
1) Localizers (2 minutes)
2) Pharmacological stress infusion (5 minutes) Adenosine at 140 mcg/kg/min for 4 minutes (or other vasodilating stress agent). Perfusion imaging at the last minute of adenosine infusion (or at the anticipated maximal hyperemic state from another agent). IV size: 18- to 22-gauge antecubital vein. Contrast injection at 4 to 5 mL/sec (5 mL/sec preferred).
3) Stress perfusion imaging (2 minutes) Sat-recovery FLASH Recommended TR/TE/ETL/slice thickness: 5 to 7 msec, 2 to 3 msec, 1 (no echo train), 10 mm Matrix 128x128, FOV 35 to 40 cm (pixel: 2.7-3.2 mm) Parallel acceleration = 2X 1 RR for at least 3 slices 0.075 to 0.1 mmol/kg injected at 4 to 5 mL/sec. Prescribe (from a diastolic 2-chamber long-axis cine) 3 slices of equally spaced short-axis cuts centered on the proximal head of papillary muscles. Basal slice and the distal slice should be at least 1 cm from the mitral ring and apex. Add a long-axis cut if heart rate allows. SSFP Recommended TR/TE/ETL/slice thickness: 3 to 4 msec, 1 to 1.5 msec, 1 (no echo train), 10 mm Same as 3a ii through 3a v
4) Top-off contrast to make up a total of 0.1 mmol/kg if necessary (1 minute)
5) Rest cine function (5 minutes) Cine SSFP short axis Recommended TR/TE: 3 to 4 msec, 1 to 1.5 msec Matrix 160x160, FOV 32 to 36 cm (pixel: 2-2.25 mm) Parallel acceleration = 2X Short-axis stack: 6-mm slice thickness and 0-mm interslice gap
6) LGE imaging Start TI scout at 10 minutes after the last contrast injection Fast GRE Recommended TR/TE: 5 to 7 msec, 3 to 4 msec Matrix 192x192 or higher, FOV 32 to 36 cm (pixel: 1.7-1.9 mm) Parallel acceleration = 2X Short-axis stack: 6-mm slice thickness and 0-mm interslice gap matching cine short-axis stack