Table 3. Allelic and genotype association testing results of rs41435250 for Mexican XFS/XFG patients and controls.
rs41435250 |
Patients (n=115) |
Controls (n=130) |
OR (95% CI) |
P |
---|---|---|---|---|
Allele | ||||
T |
35 (15.2) |
21 (8.1) |
2.0 (1.1 – 3.6) |
0.01 |
G |
195 (84.8) |
239 (91.9) |
0.49 (0.3 – 0.9) |
0.01 |
Genotype | ||||
TT |
4 (3.5) |
2 (1.5) |
2.2 (0.4 – 12.8)* |
0.3 |
GT |
27 (23.5) |
17 (13.1) |
1.9 (1.0 – 3.9)* |
0.05 |
GG | 84 (73.0) | 111 (85.4) | 0.5 (0.2 – 0.9)* | 0.02 |
Abbreviations: n=number of subjects; OR=odds ratio; CI=confidence interval. *Adjusted by gender and age.