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. 2013 Sep 24;8(9):e75811. doi: 10.1371/journal.pone.0075811

Figure 3. Metronidazole induces apoptosis in transgenically labeled cells.

Figure 3

(A-L) Head sections of mtz treated (A-D), DMSO treated (E-H) and untreated (I-L) premature adult r-opsin1::eGFP-f2A-ntr worms (eye PRCs and projections, green) processed for terminal deoxynucleotidyl transferase-mediated deoxyuridinetriphosphate nick end-labelling (TUNEL) detection (red). (A-D) Apoptosis was detected in PRCs exposed to 25mM mtz after 28 hrs incubation, whereas transgenic animals treated with DMSO alone (E-H) or transgenic untreated animals (I-L), did not show staining above background. ae: adult eye. Scale bars C: 50µm; D: 15µm.