Table 2. YAP1 expression in each histologic component of combined hepatocellular-cholangiocarcinomas (classic type).

YAP1 expression*	HCC area	CC area	Transition zone	Transition vs. HCC area	Transition vs. CC area	HCC vs. CC area
Positive	8 (27.6%)	12 (41.4%)	15 (51.7%)	0.060	0.430	0.269
Negative	21 (72.4%)	17 (58.6%)	14 (48.3%)

HCC, hepatocellular carcinoma; CC, cholangiocarcinoma

^*Nuclear YAP1 expression with moderate to strong intensities in more than 5% of the tumor cells were regarded as positive.