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. 2013 Sep 24;8(9):e75543. doi: 10.1371/journal.pone.0075543

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© 2013 Abdelmoaty et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Bar graphs showing the expression of (A) FPR2/ALX mRNA in the rat ipsilateral spinal cord plotted versus time following carrageenan injection to the hind paw, presented as a percent of mRNA levels in control (naïve) rat spinal cord. Each bar represents the mean ± S.E.M, n= 6-10. * represents a significant difference at p<0.05 as compared with naïve spinal cord. FPR2/ALX mRNA is expressed in the rat (B) and human astrocytes (C). GPR32 mRNA is expressed in human astrocytes (C). mRNA levels are expressed as relative units and each bar represents the mean ± S.E.M for three repeats. The immunohistochemical images show the expression of FPR2/ALX (D), the astrocyte marker GFAP (E) and the colocalization of FPR2/ALX and GFAP (F) in naïve rat lumbar spinal cord.