Figure 6. 17(R)-RvD1 reduced TNF-induced ERK activation in human primary astrocytes.

Bar graphs and representative western blots showing MAPK phosphorylation levels in control and TNF (50 ng/ml) stimulated cells. In astrocytes, 17(R)-RvD1 (265 nM) inhibited TNF-induced ERK (A), but not p38 (B) or JNK (C) phosphorylation. Each bar represents the mean ± S.E.M for three repeats. * represents p<0.05 for comparisons indicated in the figure.