Table 3.

Base-case analysis results

Costs per patient (US$)	Linezolid (US$)	Vancomycin (US$)	Daptomycin (US$)
Total inpatient costs	$7,835	$7,095	$7,922
Inpatient drug costs	$626	$119	$713
Drug treatment	$554	$47	$659
Drug administration	$72	$72	$54
Inpatient medical costs	$7,209	$6,976	$7,209
Hospital days	$6,068	$6,068	$6,068
ID specialist	$232	$232	$232
Adverse event costsa	$435	$201	$435
Failure costs	$474	$474	$474
Total outpatient costs	$2,736	$4,001	$5,690
Outpatient drug costs	$2,086	$634	$2,766
Drug treatment	$2,075	$487	$2,698
Drug administration	$11	$148	$68
Outpatient medical costs	$650	$3,367	$2,924
Physician visit	$246	$246	$246
Laboratory work	$34	$101	$28
OPAT costb	$285	$2,125	$1,840
PICC line and complicationsb	$85	$896	$811
Total cost of treatment	$10,571	$11,096	$13,612
Total drug costs	$2,712	$754	$3,479
Total medical costs	$7,859	$10,343	$10,133

Notes: Costs may not tally due to rounding.

^aAdverse event costs are higher for linezolid and daptomycin arm because they are assigned the vancomycin adverse event costs from empiric treatment plus any linezolid/daptomycin adverse event costs. Vancomycin is only assigned adverse event costs once;

^bOPAT and PICC line costs are incurred in the linezolid arm through treatment failures and switching to other IV antibiotics.

Abbreviations: ID, infectious disease; OPAT, outpatient parenteral antibiotic therapy; PICC, peripherally inserted central catheter; IV, intravenous.