Table II.

Diagnostic value of microRNAs for LNM in patients with cervical SCC in cancer tissue and serum.

	In cancer tissue							In serum
MicroRNA	AUC	95% CI	SE	Youden	Cut-off	Sen	Spe	AUC	95% CI	SE	Youden	Cut-off	Sen	Spe
miR-1246	0.881a	0.818–0.944	0.032	0.611	5.055	0.861	0.750	0.847a	0.767–0.927	0.041	0.575	6.010	0.715	0.860
miR-20a	0.761a	0.657–0.864	0.053	0.438	6.525	0.588	0.850	0.771a	0.664–0.878	0.055	0.504	5.050	0.604	0.900
miR-2392	0.945a	0.904–0.985	0.021	0.748	4.055	0.898	0.850	0.784a	0.695–0.872	0.045	0.444	5.000	0.744	0.700
miR-3147	0.722a	0.617–0.826	0.053	0.369	5.985	0.569	0.800	0.825a	0.748–0.903	0.040	0.521	3.975	0.821	0.700
miR-3162–5p	0.872a	0.805–0.940	0.035	0.597	5.775	0.797	0.800	0.869a	0.796–0.941	0.037	0.584	10.480	0.734	0.850
miR-4484	0.813a	0.727–0.899	0.044	0.477	9.390	0.727	0.750	0.73a	0.628–0.832	0.052	0.400	10.490	0.600	0.800
miR-4667–5p	0.737a	0.635–0.839	0.052	0.389	7.000	0.589	0.800	0.78a	0.689–0.872	0.047	0.427	6.020	0.727	0.700

Youden, maximum Youden index; Cut-off, sensitivity (Sen) and specificity (Spe) values were according to the maximum Youden index. LNM, lymph node metastasis; CI, confidence interval; AUC, area under the receiver operating characteristic (ROC) curve.

^aP<0.001.