Table 4.
Spearman partial correlation of vitamin B6 status and homocysteine with each indicator of oxidative stress and antioxidant capacity.
|
Plasma PLP (nmol/L) |
Erythrocyte PLP (pmol/g Hb) |
Plasma homocysteine (μmol/L) |
||||
|---|---|---|---|---|---|---|
| Partial r s | ||||||
| Welding exposure | Nonexposure controls | Welding exposure | Nonexposure controls | Welding exposure | Nonexposure controls | |
| Plasma homocysteine (μmol/L) |
−0.44† | −0.38* | −0.58† | −0.18 | — | — |
| Oxidative stress indicators | ||||||
| Malondialdehyde (μM) | 0.03 | 0.13 | −0.16 | 0.13 | 0.15 | −0.04 |
| Oxidized low-density lipoprotein (mU/L) | 0.04 | 0.25 | −0.06 | 0.06 | −0.04 | −0.38* |
| 8-oxo-7,8-dihydro-2′-deoxyguanosine (ng/mg creatinine) | −0.04 | 0.03 | −0.08 | 0.22 | −0.13 | 0.14 |
| Antioxidant capacities | ||||||
| Total antioxidant capacity (μM) | 0.20 | 0.09 | 0.12 | 0.04 | −0.34* | 0.08 |
| Erythrocyte glutathione (μmol/g Hb) | −0.09 | 0.14 | 0.04 | 0.15 | 0.04 | 0.19 |
| Superoxide dismutase (U/g Hb) | −0.13 | 0.10 | −0.05 | 0.41* | 0.29* | 0.28 |
| Glutathione peroxidase (nmol/min/g Hb) | −0.07 | 0.07 | 0.01 | 0.15 | 0.08 | −0.05 |
| Glutathione S-transferase (nmol/min/g Hb) |
−0.14 | −0.18 | −0.01 | −0.18 | −0.11 | 0.06 |
PLP: pyridoxal 5′-phosphate; Hb: hemoglobin. Adjusting for age, gender, albumin, creatinine, smoking, drinking, and duration of employment. *P < 0.05. **P < 0.01. † P < 0.001.