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. Author manuscript; available in PMC: 2013 Sep 25.
Published in final edited form as: Ann Intern Med. 2010 Feb 2;152(3):144–151. doi: 10.7326/0003-4819-152-3-201002020-00005

Figure 2. Time to Relapse by Treatment Arm to Week 52.

Figure 2

Note. HR = Hazard Ratio (with 95% CI); n = number of participants at risk for relapse; μR = restricted mean number of weeks to relapse (included censored observation times); the model controled for age (HR = 1.00, 95% CI: 0.99-1.01, p = 0.65), sex (HR = 0.96, 95% CI: 0.77-1.19, p = 0.69), and level of nicotine dependence. Nicotine dependence level predicted relapse from 0 to 8 weeks (HR = 1.83, 95% CI: 1.35-2.48, p < 0.001), but not from weeks 9-24 (HR = 0.91, 95% CI: 0.61-1.36, p = 0.65), or weeks 25-52 (HR = 1.04, 95% CI: 0.60-1.70, p = 0.90). The HRs were stable and uniform over the time intervals (p = 0.80). There is a residual decline in abstinence after 24 weeks, but the decline is statistically equivalent across treatment arms.