[Table/Fig-7]:
Holoprosencephalic faces
Facial typeb | Main facial features | Brain |
---|---|---|
Cyclopia | Median monophthalmia, synophthalmia, or anophthalmia. Proboscis may be single or absent. Hypognathism in some cases. | Alobar holoprosencephaly |
Ethmocephaly | Ocular hypotelorism with proboscis | Alobar holoprosencephaly |
Cebocephaly | Ocular hypotelorism and blind-ended, single- nostril nose. | Usually alobar holoprosencephaly |
Median cleft | Ocular hypotelorism, flat nose, and median cleft lip. | Usually alobar holoprosencephaly |
Less severe facial dysmorphism | Variable features including ocular hypotelorism or hypertelorism, flat nose, unilateral orbilateral cleft lip, iris coloboma, or Other anomalies. Minimal facial dysmorphism insome cases. | Semilobar or lobar holoprosencephaly |