[Table/Fig-7]:

Holoprosencephalic faces

Facial typeb	Main facial features	Brain
Cyclopia	Median monophthalmia, synophthalmia, or anophthalmia. Proboscis may be single or absent. Hypognathism in some cases.	Alobar holoprosencephaly
Ethmocephaly	Ocular hypotelorism with proboscis	Alobar holoprosencephaly
Cebocephaly	Ocular hypotelorism and blind-ended, single- nostril nose.	Usually alobar holoprosencephaly
Median cleft	Ocular hypotelorism, flat nose, and median cleft lip.	Usually alobar holoprosencephaly
Less severe facial dysmorphism	Variable features including ocular hypotelorism or hypertelorism, flat nose, unilateral orbilateral cleft lip, iris coloboma, or Other anomalies. Minimal facial dysmorphism insome cases.	Semilobar or lobar holoprosencephaly