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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Cell Microbiol. 2012 Nov 6;15(2):213–226. doi: 10.1111/cmi.12041

Figure 8. Model of a CHMP2A-CHMP3 dome-like polymer constricting a membrane bud.

Figure 8

(A) The arrangement is based on the EM reconstruction and indicates that the individual asymetric units may induce constriction via variations in their lateral interactions. Constriction is limited by the external length of the asymetric unit. (B) View inside the polymer that shows the long axis of the asymmetric unit perpendicular to the cone axis.