Table I.
qRT-PCR array analysis of ATP-binding cassette transporters.
| Gene | DLD-1 | DLDSNR6 | SNRA23F | SNRA311E | SNRD16F | SNRD38F |
|---|---|---|---|---|---|---|
| ABCA2 | 1.000 | 0.871 | 0.871 | 0.824 | 1.602 | 0.807 |
| ABCB1 | 1.000 | 6.774 | 11.314 | 17.268 | 12.295 | 7.945 |
| ABCB4 | 1.000 | 2.028 | 2.990 | 2.621 | 1.505 | 1.117 |
| ABCC1 | 1.000 | 1.141 | 1.087 | 0.914 | 0.927 | 0.883 |
| ABCC2 | 1.000 | 0.486 | 0.156 | 0.071 | 0.620 | 0.374 |
| ABCC3 | 1.000 | 0.753 | 0.901 | 0.883 | 0.835 | 0.901 |
| ABCC4 | 1.000 | 1.050 | 0.801 | 0.889 | 0.914 | 1.007 |
| ABCC5 | 1.000 | 1.035 | 1.173 | 1.240 | 1.000 | 0.841 |
| ABCC6 | 1.000 | 1.338 | 2.868 | 3.364 | 3.227 | 2.445 |
| ABCC10 | 1.000 | 1.548 | 2.085 | 2.532 | 1.753 | 2.129 |
| ABCC11 | 1.000 | 0.940 | 0.274 | 0.406 | 0.339 | 0.412 |
| ABCG2 | 1.000 | 3.031 | 6.105 | 2.497 | 9.580 | 4.199 |
qRT-PCR, quantitative reverse transcription-polymerase chain reaction. Relative expression of ATP-binding cassette transporters between the parental DLD-1 and the resistant sublines. ΔΔCt values were converted to fold-change.