Figure 2. Alignments of homologs of the yeast prionogenic protein Ure2 and Q/N-rich protein Nab2. Conserved sequences are highlighted in gray. Various types of interspersion of polyQ and polyN indicate that the observed sequences are all descended from a polyQ or polyN tract. Similar divergent interspersion patterns can be observed in PrDs and Q/N-rich domains of many other yeast proteins.