Figure 10.

MR domains involved in the interaction with MRE1.3 (A) Deletion constructs of hMR consisting of the domains A and B (AB) or the domains C, D, E, F (CDEF) were tested for their ability to increase MRE1.3 promoter activity in HEK cells (N = 3, n = 9, data represented as mean ± SEM, *P ≤ 0.05). (B) The MRE1.3 promoter activity of the MR deletion constructs used in (A) was also tested in OK cells to exclude cell-specific effects (N = 4–8, n = 12–24, data represented as mean ± SEM, *P ≤ 0.05).