Figure 12.

Influence of MR/aldosterone on regulation of promoter regions similar to MRE1.3. An immortalized proximal tubule epithelial cell line from normal adult human kidney (HK2) was transfected with hMR and incubated either with 10 nM aldosterone or vehicle for 24 h. mRNA expression levels of different genes containing promoter regions similar to MRE1.3 and judged to be of potential pathophysiological relevance by literature were detected and depicted as fold induction and ddcq. (N = 3–5, n = 3–15, data represented as mean ± SEM, *P ≤ 0.05).