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. 2013 Jul 4;41(17):8094–8106. doi: 10.1093/nar/gkt595

Figure 2.

Figure 2.

H2A.Z depletion impairs AhR-mediated activation in ERα-positive cell lines. (A) MCF7 cells were infected with shCT or shH2A.Z constructs for 5 days, then protein extraction and western blots were performed. Analysis of CYP1A1 and CYP1B1 mRNA expression was performed in ERα-positive cell lines (B) or in ERα-negative cell lines (C). The different cell lines were infected with shCT or shH2A.Z constructs for 5 days and then treated with 10 nM TCDD for 24 h.