Table 5.
Application of the simplified original RPA model to the expanded RTOG GBM (training) database
| RPA class | Median Survival | Median Survival Time | Overall Survival Rates |
||
|---|---|---|---|---|---|
| 1 year | 3 years | 5 years | |||
| III | < 50 y and KPS ≥ 90 | 17.1 months | 70% | 20% | 14% |
| IV | < 50 y and KPS < 90; | 11.2 months | 46% | 7% | 4% |
| ≥ 50 y, KPS ≥ 70, resection, and working; | |||||
| V+VI | ≥ 50 y, KPS ≥ 70, resection, and not working; | 7.5 months | 28% | 1% | 0% |
| ≥ 50 y, KPS ≥ 70, biopsy only; | |||||
| ≥ 50 y, KPS < 70 | |||||
RPA, recursive partitioning analysis; RTOG, Radiation Therapy and Oncology Group; GBM, glioblastoma multiforme; KPS, Karnofsky Performance Score.