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. Author manuscript; available in PMC: 2013 Sep 25.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2010 Oct 1;81(3):623–630. doi: 10.1016/j.ijrobp.2010.06.012

Table 5.

Application of the simplified original RPA model to the expanded RTOG GBM (training) database

RPA class Median Survival Median Survival Time Overall Survival Rates
1 year 3 years 5 years
III < 50 y and KPS ≥ 90 17.1 months 70% 20% 14%
IV < 50 y and KPS < 90; 11.2 months 46% 7% 4%
≥ 50 y, KPS ≥ 70, resection, and working;
V+VI ≥ 50 y, KPS ≥ 70, resection, and not working; 7.5 months 28% 1% 0%
≥ 50 y, KPS ≥ 70, biopsy only;
≥ 50 y, KPS < 70

RPA, recursive partitioning analysis; RTOG, Radiation Therapy and Oncology Group; GBM, glioblastoma multiforme; KPS, Karnofsky Performance Score.