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. 2010 Mar 10;2:35–42. doi: 10.4137/BIC.S3720

Table 2.

ODEs of the model.

Raf +ras gtp<->raf.ras gtp->raf* D[Ras.GTP]/dt=- k11y(11)y(12)+k12y(13)+k13y(13)
D[Raf]=-k11y(11)y(12)+k12y(13)
D[RasGTP.Raf]/dt=k11y(11)y(12)-k12y(14)-k13y(14)
D[Raf*]/dt=-k13y(13)
Raf*+mek<->raf*.mek->mek* D[Raf*]=-k14y(14)y(15)+k15y(16)+k16y(16)
D[pp2A]/dt=-k14y(14)y(14)+k15y(16)
D[Raf*.pp2A]/dt=k14y(14)y(15)-k15y(12)-k16y(12)
D[Raf]/dt=k16y(16)
Mek*+erk<->mek*.erk->erk* D[Raf*]/dt=-k17y(14)y(17)+k18y(18)+k19y(18)
D[Mek]/dt=-k17y(14)y(17)+k18y(18)
D[Raf*.Mek]/dt=k17y(14)y(17)-k18y(19)-k19y(19)
D[Mek*]/dt=-k19y(18)
Raf*+PP2A<->raf*.pp2A->raf D[Mek*]/dt=-k20y(19)y(20)+k21y(21)+k22y(21)
D[pp2A]=-k20y(19)y(20)+k21y(21)
D[Mek*.pp2A]/dt=k20y(19)y(20)-k21y(17)-k22y(17)
D[Mek]/dt=k22y(21)
Mek*+pp2A<->mek*.pp2A->mek D[Mek*]/dt=-k23y(19)y(22)+k24y(23)+k25y(23)
D[Erk]/dt=-k23y(19)y(22)+k24y(23)
D[Mek*.Erk]/dt=k23y(19)y(22)-k24y(24)-k25y(24)
D[Erk*]/dt=-k25y(23)
Erk*+mkp<->erk*.mkp->erk D[Erk*]/dt=-k26y(24)y(25)+k27y(26)+k28y(26)
D[Mkp]/dt=-k26y(24)y(25)+k27y(26)
D[Erk*.Mkp]/dt=k26y(24)y(25)-k27y(22)-k28y(22)
D[Erk]/dt=k28y(26)