Table 2.
Histopathological characteristics, chemotherapy treatment and oncological follow-up
| Case | H.P. Cystectomy | H.P. Nephroureterectomy | CT-cycles | Mets- month | Follow-up |
|---|---|---|---|---|---|
| 1 | pT1G2pN0M0 urothelial | pT4G3pN2M0 urothelial | MVEC 3 cycles | lung 1 month/liver 5 months | 5 months |
| 2 | pT3aG3pN0M0 + urothelial CIS + prostate pT2b-G2pN0M0 + urethra CIS | pT1G2pNxM0 + urothelial CIS | MVEC 3 cycles | no | 8 months |
| 3 | pT2G3pN0M1 urothelial | pT1G2pNxM1 + urothelial CIS | no | lung 1 month/liver 4 months | 5 months |
| 4 | Squamous metaplasia prostate PIN | chronic interstitial nephritis | NA | NA | NA |
| 5 | pT2G2pN0M0 urothelial | urothelial pT3bG3pNxM0 | pelvic RT | lung/med 20 months | 20 months |
| 6 | urothelial pT4aG3pN2M0, “nest type” | urothelial pT3bG3pN2M0 | CMV 6 cycles | bone 6 months/liver 7 months | 17 months |
| 7 | pT4aG3pN2M0 + urothelial CIS | urothelial pT4G3pN0M0 | MVEC 3 cycles | liver 18 months | 22 months |
| 8 | urothelial pT3bG3pN0M0 + prostate pT2bG2pN0M0 | epidermoid pT3G3pN0M0 (renal pelvis) + urothelial pT1G3pN0M0 (ureter) | CMV 6 cycles | no | 44 months |
| 9 | myxoid leiomyosarcoma pT4G3pN0M0 | myxoid leiomyosarcoma pT3G3pNxM0 | no | no; local bladder recurrence | 24 months |
| 10 | urothelial pT3aG3pN0M0 | urothelial pT1G2pN1M0 | NA | NA | NA |
| 11 | pT3aG3pN0M0 + urothelial CIS | pT3G3pNxM0 + urothelial CIS, areas of squamous differentiation | Gemcit + Cbpt 5 cycles | no | 8 months |
| 12 | urothelial pT3aG3pN0M0 + prostate PIN | renal granular cells eosino-phils pT3aG3pNxM0 | Gemcit +Cispt 2 cycles | no | 40 months |
| 13 | pT1G3pN0M0 + urothelial CIS + prostate pT2apN0M0 | renal clear cells pT1aG2-pNxM0 | no | lung 23 months | 34 months |
| 14 | pT3apN2M0 + urothelial CISm-epidermoid (35%) | pT3G3pNxM0 + urothelial CIS – squamous | Gemcit + Cbpt 4 cycles | lung 24 months | 25 months |
| 15 | bladder pT0 + prostate pT2G2pN0M0 | urothelial pT1G2pNxM0 (pelvis and ureter) | no | lung and liver 4 months | 8 months |
Cbpt = Carboplatin; Cispt = cisplatin; CMV = cisplatin, methotrexate and vinblastine; Gemcit = Gemcitabine; Liv = Liver; Med = mediastinum; MVEC = methotrexate, vinblastine, epirubicin and cisplatin; NA= no applicable.