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. 2013 Sep 26;19:2011–2022.

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Copyright © 2013 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Immunohistochemistry for X-linked inhibitor of apoptosis, Thy 1, glial fibrillary acidic protein, and 4',6-diamidino-2-phenylindole in retinal cryosections of young and old eyes at 8 days after induction of glaucoma. The merged image shows colocalization of X-linked inhibitor of apoptosis (XIAP) with Thy 1 (yellow), suggesting that the source for changes in XIAP expression is in the retinal ganglion cell (RGC) layer. A: In 3-month-old eyes, XIAP levels were increased as compared to fellow eyes. B: In old glaucomatous 13-month-old eyes, XIAP staining decreased in the RGC layer as compared to fellow eyes. Magnification 40X, scale bars: all panels 20 μm.