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. 2013 Sep 25;8(9):e75264. doi: 10.1371/journal.pone.0075264

Table 1. Patient characteristics and prevalence of DE determined with qualitative and quantitative methods.

LDS (n = 10) MFS (n = 20) Control (n = 20) Difference*
Gene abnormality TGFBR-1 or -2 FBN-1
Gender (m:f) 6∶4 12∶8 12∶8 NS
Age (y) 36.3±12.6 37.1±11.2 36.1±8.6 NS
No. of DE identified with qualitative method
DE-positive 4 (40) 16 (80) 0 (0) a, (p = 0.04); b, (p = 0.0077); c, (p<0.0001)
No. of DE identified with method-1
DE-positive 5 (50) 15 (75) 0 (0) b, (p = 0.0018); c, (p<0.0001)
No. of DE identified with method-2
DE-positive at any level 7 (70) 17 (85) 1 (5) b, (p = 0.00068); c, (p<0.0001)
L1 4 (40) 3 (15) 1 (5)
L2 3 (30) 3 (15) 0 (0)
L3 3 (30) 3 (15) 0 (0)
L4 0 (0) 4 (20) 0 (0)
L5 2 (20) 7 (35) 1 (5)
S1 6 (60) 16 (80) 0 (0)

LDS, Loeys-Dietz syndrome; MFS, Marfan syndrome; DSR, dural sac ratio; DE, dural ectasia; NS, not significant; a, difference between LDS and MFS; b, difference between LDS and control; c, difference between MFS and control.

Difference*, In this column, p values are shown. Differences were not tested for each level from L1 to S1.