Table 1. Patient characteristics and prevalence of DE determined with qualitative and quantitative methods.
LDS (n = 10) | MFS (n = 20) | Control (n = 20) | Difference* | |
Gene abnormality | TGFBR-1 or -2 | FBN-1 | ||
Gender (m:f) | 6∶4 | 12∶8 | 12∶8 | NS |
Age (y) | 36.3±12.6 | 37.1±11.2 | 36.1±8.6 | NS |
No. of DE identified with qualitative method | ||||
DE-positive | 4 (40) | 16 (80) | 0 (0) | a, (p = 0.04); b, (p = 0.0077); c, (p<0.0001) |
No. of DE identified with method-1 | ||||
DE-positive | 5 (50) | 15 (75) | 0 (0) | b, (p = 0.0018); c, (p<0.0001) |
No. of DE identified with method-2 | ||||
DE-positive at any level | 7 (70) | 17 (85) | 1 (5) | b, (p = 0.00068); c, (p<0.0001) |
L1 | 4 (40) | 3 (15) | 1 (5) | |
L2 | 3 (30) | 3 (15) | 0 (0) | |
L3 | 3 (30) | 3 (15) | 0 (0) | |
L4 | 0 (0) | 4 (20) | 0 (0) | |
L5 | 2 (20) | 7 (35) | 1 (5) | |
S1 | 6 (60) | 16 (80) | 0 (0) |
LDS, Loeys-Dietz syndrome; MFS, Marfan syndrome; DSR, dural sac ratio; DE, dural ectasia; NS, not significant; a, difference between LDS and MFS; b, difference between LDS and control; c, difference between MFS and control.
Difference*, In this column, p values are shown. Differences were not tested for each level from L1 to S1.