Table 2.
Animal models to study various aspects of TEV function
| TEV Study Feature | Animal Model |
|---|---|
| Endothelialization | sheep |
| Follow-up imaging | sheep/dog/rabbit/rat |
| TEV growth | pig/sheep |
| Patency | sheep |
| Thrombogenicity | non-human primate/sheep |
| Lipid metabolism/plaque formation | non-human primate/pig |
| Matrix materials | rat/mice |
| Cell infiltration into matrix | rat/mice |
| Thrombogenicity-microvascular | rabbit |
| Transgenic/gene manipulation | rabbit/rat/mice |
| Intimal hyperplasia (IH) | rabbit |
| Post-assessment (antibodies) | Non-human primate/dog/pig/rabbit/rat/mice |