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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Pediatr Neurol. 2013 Aug 12;49(4):237–242. doi: 10.1016/j.pediatrneurol.2013.04.009

Table 2.

Summary of Cancer and Stroke Types (N=15)

Cancer Diagnosis
until Stroke (months)
After Stroke until
Death (days)
Cancer Type Outcome WBC Count
(103/mm3)
Platelet Count
(103/mm3)
Abnormal
Coagulation
Cause of Stroke
Hemorrhagic Stroke
IP 1 Pre-T leukemia Dead 840 54 Yes Leukostasis, Thrombocytopenia, Coagulopathy/DIC
IP 1 AML Dead 52.5 28 Yes Hyperleukocytosis, Thrombocytopenia, Coagulopathy/DIC
5 5 Rhabdomyosar coma with secondary M5 AML Dead 10.2 39 No Thrombocytopenia
7 1 Acute T-cell lymphoblastic leukemia Dead 487 70 Yes Leukostasis, Coagulopathy/DIC
18 470 T-cell lymphoblastic lymphoma Dead 48 14 N/A Thrombocytopenia
19 3 Brainstem glioma Dead 4.4 30 No Thrombocytopenia
58 1 Pre-B ALL Dead 1.1 31 Yes Thrombocytopenia Coagulopathy/DIC
Hemorrhagic and Ischemic Stroke
IP 325 Anaplastic astrocytoma Dead 22 320 No Ischemic injury s/p mass effect; second stroke was idiopathic hemorrhage
Ischemic Stroke
IP 34 High grade thalamic glioma Dead 26 311 Yes Ischemic injury s/p tumor mass effect
IP 409 Grade 4 glioma, cerebellopontine angle Dead 17 237 No Ischemic injury s/p tumor mass effect
58 N/A AML with CNS relapse Alive 40 369 No CNS relapse of leukemia presenting as diffuse ischemic stroke
43 34 Recurrent anaplastic astrocytoma with secondary AML Dead 4.5 8 Yes Ischemic stroke due to radiation induced vasculopathy
CSVT
1 N/A Pre-B ALL Alive 1.2 90 No CSVT after L-asparaginase with ischemic venous infarction
IP 256 Burkitt lymphoma Dead 11.5 207 No CSVT due to tumoral infiltrative process
10 181 ALL Dead 5.9 167 No CSVT after L-asparaginase with ischemic venous infarction

Abbreviations:

ALL = acute lymphoblastic leukemia

AML = acute myelogenous leukemia

CNS = central nervous system

CSVT = cerebral sinovenous thrombosis

DIC = disseminated intravascular coagulation

IP = initial presentation

N/A = not applicable

s/p = suspected

WBC = white blood cell