Table 2.
Cancer Diagnosis until Stroke (months) |
After Stroke until Death (days) |
Cancer Type | Outcome | WBC Count (103/mm3) |
Platelet Count (103/mm3) |
Abnormal Coagulation |
Cause of Stroke |
---|---|---|---|---|---|---|---|
Hemorrhagic Stroke | |||||||
IP | 1 | Pre-T leukemia | Dead | 840 | 54 | Yes | Leukostasis, Thrombocytopenia, Coagulopathy/DIC |
IP | 1 | AML | Dead | 52.5 | 28 | Yes | Hyperleukocytosis, Thrombocytopenia, Coagulopathy/DIC |
5 | 5 | Rhabdomyosar coma with secondary M5 AML | Dead | 10.2 | 39 | No | Thrombocytopenia |
7 | 1 | Acute T-cell lymphoblastic leukemia | Dead | 487 | 70 | Yes | Leukostasis, Coagulopathy/DIC |
18 | 470 | T-cell lymphoblastic lymphoma | Dead | 48 | 14 | N/A | Thrombocytopenia |
19 | 3 | Brainstem glioma | Dead | 4.4 | 30 | No | Thrombocytopenia |
58 | 1 | Pre-B ALL | Dead | 1.1 | 31 | Yes | Thrombocytopenia Coagulopathy/DIC |
Hemorrhagic and Ischemic Stroke | |||||||
IP | 325 | Anaplastic astrocytoma | Dead | 22 | 320 | No | Ischemic injury s/p mass effect; second stroke was idiopathic hemorrhage |
Ischemic Stroke | |||||||
IP | 34 | High grade thalamic glioma | Dead | 26 | 311 | Yes | Ischemic injury s/p tumor mass effect |
IP | 409 | Grade 4 glioma, cerebellopontine angle | Dead | 17 | 237 | No | Ischemic injury s/p tumor mass effect |
58 | N/A | AML with CNS relapse | Alive | 40 | 369 | No | CNS relapse of leukemia presenting as diffuse ischemic stroke |
43 | 34 | Recurrent anaplastic astrocytoma with secondary AML | Dead | 4.5 | 8 | Yes | Ischemic stroke due to radiation induced vasculopathy |
CSVT | |||||||
1 | N/A | Pre-B ALL | Alive | 1.2 | 90 | No | CSVT after L-asparaginase with ischemic venous infarction |
IP | 256 | Burkitt lymphoma | Dead | 11.5 | 207 | No | CSVT due to tumoral infiltrative process |
10 | 181 | ALL | Dead | 5.9 | 167 | No | CSVT after L-asparaginase with ischemic venous infarction |
Abbreviations:
ALL = acute lymphoblastic leukemia
AML = acute myelogenous leukemia
CNS = central nervous system
CSVT = cerebral sinovenous thrombosis
DIC = disseminated intravascular coagulation
IP = initial presentation
N/A = not applicable
s/p = suspected
WBC = white blood cell